Developing methods and theories for Big Data analysis and addressing the challenges of the digital revolution: these are the objectives of the Master’s degree course in Physics of Data, aimed at training a new generation of physicists capable of combining advanced skills in physics with a solid background in Data Science and Machine Learning. As physics interprets complex phenomena that require the acquisition and processing of large amounts of data, there is a growing need to train experts who can also develop specific tools to analyze them. The course, entirely in English, includes mandatory internship activities for research initiation, to be carried out in research centers or private companies. Graduates with a Master’s degree in Physics of Data will acquire skills to describe and model complex data and systems using modern techniques, develop good problem-solving and teamwork abilities, and cultivate a strong interdisciplinary aptitude.